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Farmasötik Teknoloji AbD.

Esra PEZİK, Dr. Öğr. Üyesi

Arş. Gör. Esra Pezik, Gazi Üniversitesi Eczacılık Fakültesi mezunudur. Lisans eğitimini tamamladıktan sonra 2016 yılında Hacettepe Üniversitesi Eczacılık Fakültesi Farmasötik Teknoloji Anabilim Dalı’nda doktora eğitimine başlamış olup halen devam etmektedir. Pezik’in SCI indeksli dergilerde yayımlanmış 1 adet araştırma makalesi vardır.


Çalışma Alanları: Eczacılık, Eczacılık Teknolojisi, Farmasötik Teknoloji, Nanokristal Teknolojisi, Ağızda Dağılan Filmler

Makaleler

MAKALELER

    • Pezik, E., Gülsün, T., Sahin, S., Vural, İ. (2021). Development and characterization of pullulan-based orally disintegrating films containing amlodipine besylate. European Journal of Pharmaceutical Sciences, 156:105597.
    • Pınar, S.G., Pezik, E., Ağardan, B.M., Çelebi, N. (2022). Development of cyclosporine A nanosuspension: Cytotoxicity and permeability on Caco-2 cell lines. Pharmaceutical Development and Technology, 27(1):52-62.
    • Özemre, G.R., Kara, A., Pezik, E., Tort, S., Vural, İ., Acartürk, F. (2023). Preparation of nanofibers and nanoparticle loaded nanofibers for oral administration of low molecular weight Heparin. Journal of Drug Delivery Science and Technology, 79:104068.
    • Gültekin, Y., Öztürk, N., Filazi, A., Deniz, A., Korkmaz, Ç., Pezik, E., Barın, G., Vural, İ. (2022). Simultaneous determination of albendazole sulfoxide and praziquantel from PLGA nanoparticles and validation of new HPLC method. Journal of Research in Pharmacy, 26(6): 1608-1618
    • Gültekin, Y., Öztürk, N., Filazi, A., Deniz, A., Korkmaz, Ç., Pezik, E., Barın, G., Vural, İ. (2022). Simultaneous determination of albendazole sulfoxide and praziquantel from PLGA nanoparticles and validation of new HPLC method. Journal of Research in Pharmacy, 26(6): 1608-1618

BILDIRILER

    • Gültekin, Y., Öztürk, N., Sahin, G., Pezik, E., Kara, A., Vural, İ. (2021). A new orodıspersıble tablet formulatıon of an antıhypertensıve drug. 13th International Symposium on Pharmaceutical Sciences (ISOPS) Virtual Meeting, 22-25 Haziran 2021.
    • Pezik, E., Gülsün, T., Gündüz, M.G., Sahin, S., Vural, İ. (2022). Investigation of the effect of freeze drying with different cryoprotectants on in-vitro cytotoxicity of M3 nanocrystals. 20th International Pharmaceutical Technology Symposium (IPTS) Virtual Meeting, 21-23 Şubat 2022.
    • Öztürk, N., Kara, A., Pezik, E., Vural, İ. (2022). In vitro evaluation of doxorubicin and telmisartan loaded lipid-PLGA hybrid nanoparticles on breast cancer cells. 20th International Pharmaceutical Technology Symposium (IPTS) Virtual Meeting, 21-23 Şubat 2022.
    • Pezik, E., Öztürk, N., Vural, İ. (2017). Orally disintegrating tablets of telmisartan; Formulation development and evaluation. 2nd International Gazi Pharma Symposium Series (GPSS), 11-13 Ekim 2017, Ankara – Türkiye.
    • Pezik, E., Öztürk, N., Kara, A., Vural, İ. (2017). Pullulan based orally disintegrating films of telmisartan. 2nd International Gazi Pharma Symposium Series (GPSS), 11-13 Ekim 2017, Ankara – Türkiye..
    • Pezik, E., Öztürk, N., Sahin, S., Vural, İ. (2018). Determination of cytotoxicity of lamotrigine on L929 cell line. 12th International Symposium on Pharmaceutical Sciences (ISOPS), 26-29 Haziran 2018, Ankara – Türkiye.
    • Pezik, E., Öztürk, N., Çeliker, A., Sahin, S., Vural, İ. (2018). Effect of lamotrigine on viability of MCF-7 and RG-2 cells. 19th International Pharmaceutical Technology Symposium (IPTS), 17-19 Eylül 2018, Antalya – Türkiye.
    • Pezik, E., Öztürk, N., Sahin, S., Vural, İ. (2019). Determination of equilibrium solubility of lamotrigine using UV spectrophotometer. International Multidisciplinary Symposium on Drug Research and Development (DRD), 1-3 Temmuz 2019, Malatya – Türkiye.
    • Pezik, E., Sahin, S., Vural, İ. (2019). Development and evaluation of orally disintegrating films containing amlodipine besylate. 8th International Conference on Pharmaceutical Sciences (BBBB), 14-16 Ekim 2019, İzmir – Türkiye.
    • Pezik, E., Sahin, S., Vural, İ. (2019). Development and validation of UV spectrophotometric method for in vitro dissolution studies of orally disintegrating films containing amlodipine besylate. 8th International Conference on Pharmaceutical Sciences (BBBB), 14-16 Ekim 2019, İzmir – Türkiye.
    • Pezik, E., Sahin, S., Vural, İ. (2019). Development and validation of UV spectrophotometric method for determination of amlodipine besylate in orally disintegrating films. 8th International Conference on Pharmaceutical Sciences (BBBB), 14-16 Ekim 2019, İzmir – Türkiye.
    • Pezik, E., Sahin, S., Vural, İ. (2019). In vitro cytotoxicity studies of orally disintegrating films containing amlodipine besylate. 8th International Conference on Pharmaceutical Sciences (BBBB), 14-16 Ekim 2019, İzmir – Türkiye.
    • E Pezik, E., Sahin, S., Vural, İ. (2019). Determination of equilibrium solubility of amlodipine besylate. 8th International Conference on Pharmaceutical Sciences (BBBB), 14-16 Ekim 2019, İzmir – Türkiye.
    • E Pezik, E., Sahin, S., Vural, İ. (2019). Development and evaluation of UV spectrophotometric method for solubility studies of amlodipine besylate. 8th International Conference on Pharmaceutical Sciences (BBBB), 14-16 Ekim 2019, İzmir – Türkiye.
    • Pezik, E., Gülsün, T., Gündüz, M.G., Sahin, S., Vural, İ. (2021). M3 nanosuspensions preparing by combination of precipitation and ultrasonication methods. European Federation for Pharmaceutical Sciences (EUFEPS) Virtual Annual Meeting, 7-9 Haziran 2021.
    • Pezik, E., Gültekin, Y., Gülsün, T., Sahin, S., Vural, İ. (2021). Preparation of lamotrigine solid dispersions with different polymeric and surfactant carriers to enhance solubility. 13th International Symposium on Pharmaceutical Sciences (ISOPS) Virtual Meeting, 22-25 Haziran 2021.
    • Pezik, E., Gültekin, Y., Gülsün, T., Sahin, S., Vural, İ. (2021). Development and validation of an HPLC method for determination of lamotrigine in solid dispersion.13th International Symposium on Pharmaceutical Sciences (ISOPS Virtual Meeting, 22-25 Haziran 2021.
    • Çopur, T., Yalçın, D., Kurt, N., Pezik, E., Pehlivan, S.B., Öner, L. (2021). Design of ketorolac tromethamine loaded nanoparticles and evaluation of in vitro effıciency for brain tumor treatment. 13th International Symposium on Pharmaceutical Sciences (ISOPS) Virtual Meeting, 22-25 Haziran 2021.
    • Çopur, T., Yalçın, D., Kurt, N., Pezik, E., Pehlivan, S.B., Öner, L. (2021). The effect of freeze drying with different cryoprotectants on the characteristics of ketorolac tromethamine loaded nanoparticles. 13th International Symposium on Pharmaceutical Sciences (ISOPS Virtual Meeting, 22-25 Haziran 2021.
    • Pezik, E., Gülsün, T., Gündüz, M.G., Sahin, S., Vural, İ. (2021). Development and validation of An HPLC method for the analysis of a newly synthesized 1,4-dihydropyridine derivative (M3). Controlled Release Society (CRS) Virtual Annual Meeting, 25-29 Temmuz 2021.
    • Pezik, E., Gülsün, T., Gündüz, M.G., Sahin, S., Vural, İ. (2021). Determination of BCS class of a new antihypertensive drug candidate (M3) according to Biopharmaceutical Classification System. Controlled Release Society (CRS) Virtual Annual Meeting, 25-29 Temmuz 2021.
    • Pezik, E., Çopur, T., Pehlivan, S.B., Sahin, S., Öner, L., Vural, İ. (2021). Preparation of carbamazepine solid dispersions and determination of solubility. 3rd International Gazi Pharma Symposium Series (GPSS) Virtual Meeting, 8-10 Eylül 2021.
    • Pezik, E., Çopur, T., Pehlivan, S.B., Sahin, S., Öner, L., Vural, İ. (2021). Determination of the effects of different carriers on in vitro cytotoxicity of carbamazepine solid dispersions. 3rd International Gazi Pharma Symposium Series (GPSS) Virtual Meeting, 8-10 Eylül 2021.
    • Pezik, E., Sahin, S., Vural, İ. (2022). Evaluation of the effects of different carriers on the in vitro cytotoxicity of lamotrigine solid dispersions. 20th International Pharmaceutical Technology Symposium (IPTS) Virtual Meeting, 21-23 Şubat 2022.
    • Pezik, E., Gülsün, T., Gündüz, M.G., Sahin, S., Vural, İ. (2022). Effect of M3 nanocrystals on the viability of Caco-2, SK-BR-3, MCF-7 and A549 cells. 20th International Pharmaceutical Technology Symposium (IPTS) Virtual Meeting, 21-23 Şubat 2022.
    • Gültekin, Y., Barın, G., Pezik, E., Öztürk, N., Vural, İ. (2022). Preparation of trandolapril β-cyclodextrin inclusion complex for increasing trandolapril solubility. 20th International Pharmaceutical Technology Symposium (IPTS) Virtual Meeting, 21-23 Şubat 2022.
    • Gültekin, Y., Öztürk, N., Filazi, A., Deniz, A., Korkmaz, Ç., Pezik, E., Barın, G., Vural, İ. (2022). Development and validation of a new HPLC method for the simultaneous determination of albendazol sulfoxide and praziquantel from PLGA nanoparticles. 20th International Pharmaceutical Technology Symposium (IPTS) Virtual Meeting, 21-23 Şubat 2022.
    • Pezik, E., Gülsün, T., Gündüz, M.G., Sahin, S., Vural, İ. (2022). The effect of different stabilizers on in-vitro cytotoxicity of M3 nanocrystals. 10th International Drug Chemistry Congress, 9-12 Mart 2022, Antalya – Türkiye.
Kitaplar
  • Barın, G., Gültekin, Y., Pezik, E., Öztürk, N., Kara, A., Vural, İ. (2021). Chapter 10: Cellular uptake and transcytosis. Çapan, Y., Şahin, A., Tonbul, H., Editörler, Jenny Stanford Publishing Pte. Ltd.:Florida; 2021, ss. 247-279
Projeler
  • Hipertansiyon tedavisinde etkili yeni sentezlenen ve çözünürlük sorunu olan 1,4-dihidropiridin türevli madde üzerinde önformülasyon çalışmaları. Hacettepe Üniversitesi Bilimsel Araştırma Projeleri, Hızlı Destek Projesi, Proje Yürütücüsü: Prof. Dr. İmran Vural, Araştırmacılar: Prof. Dr. Selma Şahin, Doç. Dr. Miyase Gözde Gündüz, Dr. Öğr. Üyesi Tuğba Gülsün İnal, Esra Pezik (21.11.2019 – 21.10.2022).
  • Fitaz enzimi ile hedeflendirilmiş albendazol sülfoksit ve praziquantel yüklü nanotaşıyıcıların Echinococcus granulosus kistlerine in vitro etkinliğinin değerlendirilmesi. Hacettepe Üniversitesi Bilimsel Araştırma Projeleri, Kapsamlı Araştırma Projesi, Proje Yürütücüsü: Prof. Dr. İmran Vural, Araştırmacılar: Prof. Dr. Ayhan Filazi, Doç. Dr. Ahmet Deniz, Dr. Öğr. Naile Öztürk, Esra Pezik, Bursiyerler: Yakup Gültekin, Gözde Barın, Çağla Korkmaz (28.09.2021 – Devam Ediyor).